Journalartikel

Facts, myths and hypotheses on the zoonotic nature of Mycobacterium avium subspecies paratuberculosis


AutorenlisteAtreya, Raja; Buelte, Michael; Gerlach, Gerald-F.; Goethe, Ralph; Hornef, Mathias W.; Koehler, Heike; Meens, Jochen; Moebius, Petra; Roeb, Elke; Weiss, Siegfried

Jahr der Veröffentlichung2014

Seiten858-867

ZeitschriftInternational Journal of Medical Microbiology

Bandnummer304

Heftnummer7

ISSN1438-4221

eISSN1618-0607

DOI Linkhttps://doi.org/10.1016/j.ijmm.2014.07.006

VerlagElsevier


Abstract
Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of paratuberculosis (Johne's disease [JD]), a chronic granulomatous enteritis in ruminants. JD is one of the most widespread bacterial diseases of domestic animals with significant economic impact. The histopathological picture of JD resembles that of Crohn's disease (CD), a human chronic inflammatory bowel disease of still unresolved aetiology. An aetiological relevance of MAP for CD has been proposed. This and the ambiguity of other published epidemiological findings raise the question whether MAP represents a zoonotic agent. In this review, we will discuss evidence that MAP has zoonotic capacity. (C) 2014 Elsevier GmbH. All rights reserved.



Zitierstile

Harvard-ZitierstilAtreya, R., Buelte, M., Gerlach, G., Goethe, R., Hornef, M., Koehler, H., et al. (2014) Facts, myths and hypotheses on the zoonotic nature of Mycobacterium avium subspecies paratuberculosis, International Journal of Medical Microbiology, 304(7), pp. 858-867. https://doi.org/10.1016/j.ijmm.2014.07.006

APA-ZitierstilAtreya, R., Buelte, M., Gerlach, G., Goethe, R., Hornef, M., Koehler, H., Meens, J., Moebius, P., Roeb, E., & Weiss, S. (2014). Facts, myths and hypotheses on the zoonotic nature of Mycobacterium avium subspecies paratuberculosis. International Journal of Medical Microbiology. 304(7), 858-867. https://doi.org/10.1016/j.ijmm.2014.07.006



Schlagwörter


BOVINE EPITHELIAL-CELLSCrohn's diseaseFRAGMENT-LENGTH-POLYMORPHISMIN-SITU HYBRIDIZATIONMycobacterium aviumNATURALLY INFECTED CATTLESHORT-SEQUENCE-REPEATSMALL-INTESTINAL MUCOSA


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