Journal article

Facts, myths and hypotheses on the zoonotic nature of Mycobacterium avium subspecies paratuberculosis


Authors listAtreya, Raja; Buelte, Michael; Gerlach, Gerald-F.; Goethe, Ralph; Hornef, Mathias W.; Koehler, Heike; Meens, Jochen; Moebius, Petra; Roeb, Elke; Weiss, Siegfried

Publication year2014

Pages858-867

JournalInternational Journal of Medical Microbiology

Volume number304

Issue number7

ISSN1438-4221

eISSN1618-0607

DOI Linkhttps://doi.org/10.1016/j.ijmm.2014.07.006

PublisherElsevier


Abstract
Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of paratuberculosis (Johne's disease [JD]), a chronic granulomatous enteritis in ruminants. JD is one of the most widespread bacterial diseases of domestic animals with significant economic impact. The histopathological picture of JD resembles that of Crohn's disease (CD), a human chronic inflammatory bowel disease of still unresolved aetiology. An aetiological relevance of MAP for CD has been proposed. This and the ambiguity of other published epidemiological findings raise the question whether MAP represents a zoonotic agent. In this review, we will discuss evidence that MAP has zoonotic capacity. (C) 2014 Elsevier GmbH. All rights reserved.



Citation Styles

Harvard Citation styleAtreya, R., Buelte, M., Gerlach, G., Goethe, R., Hornef, M., Koehler, H., et al. (2014) Facts, myths and hypotheses on the zoonotic nature of Mycobacterium avium subspecies paratuberculosis, International Journal of Medical Microbiology, 304(7), pp. 858-867. https://doi.org/10.1016/j.ijmm.2014.07.006

APA Citation styleAtreya, R., Buelte, M., Gerlach, G., Goethe, R., Hornef, M., Koehler, H., Meens, J., Moebius, P., Roeb, E., & Weiss, S. (2014). Facts, myths and hypotheses on the zoonotic nature of Mycobacterium avium subspecies paratuberculosis. International Journal of Medical Microbiology. 304(7), 858-867. https://doi.org/10.1016/j.ijmm.2014.07.006



Keywords


BOVINE EPITHELIAL-CELLSCrohn's diseaseFRAGMENT-LENGTH-POLYMORPHISMIN-SITU HYBRIDIZATIONMycobacterium aviumNATURALLY INFECTED CATTLESHORT-SEQUENCE-REPEATSMALL-INTESTINAL MUCOSA

Last updated on 2025-21-05 at 18:36