Journalartikel

Jahr der Veröffentlichung: 2014

Seiten: 1189-1197

Zeitschrift: Andrologia

Bandnummer: 46

Heftnummer: 10

ISSN: 0303-4569

eISSN: 1439-0272

Open Access Status: Gold

DOI Link: https://doi.org/10.1111/and.12215

Verlag: Wiley

Abstract: 
As commonly used self-reported screening instruments for male hypogonadism demonstrated lack of specificity, a Hypogonadism Related Symptom Scale (HRS) was developed in 2009 as a novel self-rating screening tool. As the questionnaire has not been validated, the purpose of our study was to perform a validation in patients presenting with different disorders (e.g. infertility, HIV infection or metabolic syndrome) and disease-related risk to develop hypogonadism. Two hundred and eighteen patients aged 19-71years (40.1 +/- 9.5) who completed the HRS and other common questionnaires [International Index Of Erectile Function (IIEF), National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI), Hospital Anxiety and Depression Scale (HADS), short form (SF)-12] were included. In all patients, blood levels of total testosterone, luteinizing hormone, follicle-stimulating hormone, oestradiol and sex hormone-binding globulin were determined and free testosterone was calculated. Cronbach's for the scale was 0.896, split-half 0.871 for the 1st half and 0.807 for the 2nd half. Spearman-Brown coefficient was 0.767, and Guttman split-half coefficient was 0.759. Consistent correlations were found between HRS and IIEF5 (=0.57, P<0.001), and HADS (=-0.6, P<0.001). In addition, HRS was significantly correlated with total testosterone (=0.135, P<0.05), free testosterone (=0.148, P<0.05) and oestradiol (=-0.134, P<0.05). Our validation study confirms the data from the initial development of the HRS questionnaire. Clinicians might have an additional advantage from the HRS when investigating males with suspected hypogonadism.

Harvard-Zitierstil: Alidjanov, J., Wolf, J., Schuppe, H., Weidner, W., Diemer, T., Linn, T., et al. (2014) Validation of the German version of the 'Hypogonadism Related Symptom Scale' (HRS) in andrological patients with infertility, HIV infection and metabolic syndrome, Andrologia, 46(10), pp. 1189-1197. https://doi.org/10.1111/and.12215

APA-Zitierstil: Alidjanov, J., Wolf, J., Schuppe, H., Weidner, W., Diemer, T., Linn, T., Halefeldt, I., Wagenlehner, F., Wiltink, J., & Pilatz, A. (2014). Validation of the German version of the 'Hypogonadism Related Symptom Scale' (HRS) in andrological patients with infertility, HIV infection and metabolic syndrome. Andrologia. 46(10), 1189-1197. https://doi.org/10.1111/and.12215