Journal article

A single center comparison between three different apheresis systems for autologous and allogeneic stem cell collections


Authors listFlommersfeld, Sabine; Bakchoul, Tamam; Bein, Gregor; Wachtel, Almut; Loechelt, Cordula; Sachs, Ulrich J.

Publication year2013

Pages428-433

JournalTransfusion and Apheresis Science

Volume number49

Issue number3

ISSN1473-0502

DOI Linkhttps://doi.org/10.1016/j.transci.2013.06.002

PublisherElsevier


Abstract
Three different apheresis systems were used in our center for the collection of peripheral blood progenitor cells (PBPCs): COM.TEC (Fresenius Healthcare), CUBE Spectra, and Spectra Optia (both from Caridian BCT). We compared 131 autologous and 56 allogeneic apheresis procedures to elucidate feasibility and effectiveness of the different systems. Collection efficiacy varied significantly with lowest results obtained with CUBE Spectra. COM.TEC and Spectra Optia produced lower WBC contamination than CUBE Spectra, but at the expense of higher product volume and longer apheresis time. High collection efficacy and a low product volume may be favorable characteristics of the Spectra Optia. (C) 2013 Elsevier Ltd. All rights reserved.



Citation Styles

Harvard Citation styleFlommersfeld, S., Bakchoul, T., Bein, G., Wachtel, A., Loechelt, C. and Sachs, U. (2013) A single center comparison between three different apheresis systems for autologous and allogeneic stem cell collections, Transfusion and Apheresis Science, 49(3), pp. 428-433. https://doi.org/10.1016/j.transci.2013.06.002

APA Citation styleFlommersfeld, S., Bakchoul, T., Bein, G., Wachtel, A., Loechelt, C., & Sachs, U. (2013). A single center comparison between three different apheresis systems for autologous and allogeneic stem cell collections. Transfusion and Apheresis Science. 49(3), 428-433. https://doi.org/10.1016/j.transci.2013.06.002



Keywords


Apheresis proceduresBLOOD PROGENITOR CELLSBONE-MARROWCollection efficacyCOUNTSPROTOCOLSSEPARATORSStem cell collectionTRANSPLANTATION

Last updated on 2025-02-04 at 02:20