Journalartikel

Apoptosis signaling in influenza virus propagation, innate host defense, and lung injury


AutorenlisteHerold, Susanne; Ludwig, Stephan; Pleschka, Stephan; Wolff, Thorsten

Jahr der Veröffentlichung2012

Seiten75-82

ZeitschriftJournal of Leukocyte Biology

Bandnummer92

Heftnummer1

ISSN0741-5400

eISSN1938-3673

DOI Linkhttps://doi.org/10.1189/jlb.1011530

VerlagOxford University Press


Abstract
Programmed cell death is a crucial cellular response frequently observed in IV-infected tissue. This article reviews the current knowledge on the molecular virus-host interactions that induce apoptosis pathways in an IV-infected cell and the functional implications of these cellular signaling events on viral propagation at distinct steps during the viral replication cycle. Furthermore, it summarizes the role of IV-induced apoptosis pathways in equilibrating the host's antiviral immune response between effective viral clearance and development of severe apoptotic lung injury. J. Leukoc. Biol. 92: 75-82; 2012.



Zitierstile

Harvard-ZitierstilHerold, S., Ludwig, S., Pleschka, S. and Wolff, T. (2012) Apoptosis signaling in influenza virus propagation, innate host defense, and lung injury, Journal of Leukocyte Biology, 92(1), pp. 75-82. https://doi.org/10.1189/jlb.1011530

APA-ZitierstilHerold, S., Ludwig, S., Pleschka, S., & Wolff, T. (2012). Apoptosis signaling in influenza virus propagation, innate host defense, and lung injury. Journal of Leukocyte Biology. 92(1), 75-82. https://doi.org/10.1189/jlb.1011530



Schlagwörter


ARDSA-VIRUSCD8 T-CELLSFAS-LIGANDINFECTED-CELLSNS1PB1-F2PROGRAMMED CELL-DEATHPROTEIN INDUCES APOPTOSISTRAILviralVIRAL NS1 PROTEIN


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