Journal article
Authors list: Herold, Susanne; Ludwig, Stephan; Pleschka, Stephan; Wolff, Thorsten
Publication year: 2012
Pages: 75-82
Journal: Journal of Leukocyte Biology
Volume number: 92
Issue number: 1
ISSN: 0741-5400
eISSN: 1938-3673
DOI Link: https://doi.org/10.1189/jlb.1011530
Publisher: Oxford University Press
Abstract:
Programmed cell death is a crucial cellular response frequently observed in IV-infected tissue. This article reviews the current knowledge on the molecular virus-host interactions that induce apoptosis pathways in an IV-infected cell and the functional implications of these cellular signaling events on viral propagation at distinct steps during the viral replication cycle. Furthermore, it summarizes the role of IV-induced apoptosis pathways in equilibrating the host's antiviral immune response between effective viral clearance and development of severe apoptotic lung injury. J. Leukoc. Biol. 92: 75-82; 2012.
Citation Styles
Harvard Citation style: Herold, S., Ludwig, S., Pleschka, S. and Wolff, T. (2012) Apoptosis signaling in influenza virus propagation, innate host defense, and lung injury, Journal of Leukocyte Biology, 92(1), pp. 75-82. https://doi.org/10.1189/jlb.1011530
APA Citation style: Herold, S., Ludwig, S., Pleschka, S., & Wolff, T. (2012). Apoptosis signaling in influenza virus propagation, innate host defense, and lung injury. Journal of Leukocyte Biology. 92(1), 75-82. https://doi.org/10.1189/jlb.1011530
Keywords
ARDS; A-VIRUS; CD8 T-CELLS; FAS-LIGAND; INFECTED-CELLS; NS1; PB1-F2; PROGRAMMED CELL-DEATH; PROTEIN INDUCES APOPTOSIS; TRAIL; viral; VIRAL NS1 PROTEIN
