Konferenzpaper

The neuroimmune connection interferes with tissue regeneration and chronic inflammatory disease in the skin


AutorenlistePeters, Eva M. J.; Liezmann, Christiane; Klapp, Burghard F.; Kruse, Johannes

HerausgeberlisteDelRey, A; Welsh, CJ; Schwarz, MJ; Besedovsky, HO

Jahr der Veröffentlichung2012

Seiten118-126

ZeitschriftAnnals of the New York Academy of Sciences

Bandnummer1262

ISSN0077-8923

eISBN978-1-57331-899-0

DOI Linkhttps://doi.org/10.1111/j.1749-6632.2012.06647.x

Konferenz8th Congress of the International-Society-for-Neuroimmunomodulation (ISNIM)/German Endocrine-Brain-Immune Network (GEBIN)

VerlagWiley

SerientitelAnnals of the New York Academy of Sciences


Abstract
Research over the past decades has revealed close interactions between the nervous and immune systems that regulate peripheral inflammation and link psychosocial stress with chronic somatic disease. Besides activation of the sympathetic and the hypothalamus-pituitary-adrenal axis, stress leads to increased neurotrophin and neuropeptide production in organs at the self-environment interface. The scope of this short review is to discuss key functions of these stress mediators in the skin, an exemplary stress-targeted and stress-sensitive organ. We will focus on the skin's response to acute and chronic stress in tissue regeneration and pathogenesis of allergic inflammation, psoriasis, and skin cancer to illustrate the impact of local stress-induced neuroimmune interaction on chronic inflammation.



Zitierstile

Harvard-ZitierstilPeters, E., Liezmann, C., Klapp, B. and Kruse, J. (2012) The neuroimmune connection interferes with tissue regeneration and chronic inflammatory disease in the skin, Annals of the New York Academy of Sciences, 1262, pp. 118-126. https://doi.org/10.1111/j.1749-6632.2012.06647.x

APA-ZitierstilPeters, E., Liezmann, C., Klapp, B., & Kruse, J. (2012). The neuroimmune connection interferes with tissue regeneration and chronic inflammatory disease in the skin. Annals of the New York Academy of Sciences. 1262, 118-126. https://doi.org/10.1111/j.1749-6632.2012.06647.x



Schlagwörter


CORTICOTROPIN-RELEASING HORMONEHUMAN HAIR FOLLICLEMALIGNANT-MELANOMANERVE GROWTH-FACTORNEUROGENIC INFLAMMATIONneuroimmune plasticityneuroimmunologyNEUROTROPHIC FACTORneurotrophin/neuropeptide stress axispsychodermatologySTRESS-INDUCED ENDOCRINESUBSTANCE-P


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