Conference paper

Editor list: DelRey, A; Welsh, CJ; Schwarz, MJ; Besedovsky, HO

Publication year: 2012

Pages: 118-126

Journal: Annals of the New York Academy of Sciences

Volume number: 1262

ISSN: 0077-8923

eISBN: 978-1-57331-899-0

DOI Link: https://doi.org/10.1111/j.1749-6632.2012.06647.x

Conference: 8th Congress of the International-Society-for-Neuroimmunomodulation (ISNIM)/German Endocrine-Brain-Immune Network (GEBIN)

Publisher: Wiley

Title of series: Annals of the New York Academy of Sciences

Abstract: 
Research over the past decades has revealed close interactions between the nervous and immune systems that regulate peripheral inflammation and link psychosocial stress with chronic somatic disease. Besides activation of the sympathetic and the hypothalamus-pituitary-adrenal axis, stress leads to increased neurotrophin and neuropeptide production in organs at the self-environment interface. The scope of this short review is to discuss key functions of these stress mediators in the skin, an exemplary stress-targeted and stress-sensitive organ. We will focus on the skin's response to acute and chronic stress in tissue regeneration and pathogenesis of allergic inflammation, psoriasis, and skin cancer to illustrate the impact of local stress-induced neuroimmune interaction on chronic inflammation.

Harvard Citation style: Peters, E., Liezmann, C., Klapp, B. and Kruse, J. (2012) The neuroimmune connection interferes with tissue regeneration and chronic inflammatory disease in the skin, Annals of the New York Academy of Sciences, 1262, pp. 118-126. https://doi.org/10.1111/j.1749-6632.2012.06647.x

APA Citation style: Peters, E., Liezmann, C., Klapp, B., & Kruse, J. (2012). The neuroimmune connection interferes with tissue regeneration and chronic inflammatory disease in the skin. Annals of the New York Academy of Sciences. 1262, 118-126. https://doi.org/10.1111/j.1749-6632.2012.06647.x