Journalartikel

Intermedin (adrenomedullin2) stabilizes the endothelial barrier and antagonizes thrombin-induced barrier failure in endothelial cell monolayers


AutorenlisteAslam, M.; Pfeil, U.; Guenduez, D.; Rafiq, A.; Kummer, W.; Piper, H. M.; Noll, T.

Jahr der Veröffentlichung2012

Seiten208-222

ZeitschriftBritish Journal of Pharmacology

Bandnummer165

Heftnummer1

ISSN0007-1188

Open Access StatusGreen

DOI Linkhttps://doi.org/10.1111/j.1476-5381.2011.01540.x

VerlagWiley


Abstract
BACKGROUND AND PURPOSE Intermedin is a member of the calcitonin gene-related-peptide (CGRP) family expressed in endothelial cells and acts via calcitonin receptor-like receptors (CLRs). Here we have analysed the receptors for intermedin and its effect on the endothelial barrier in monolayers of human umbilical vein endothelial cells (HUVECs).



Zitierstile

Harvard-ZitierstilAslam, M., Pfeil, U., Guenduez, D., Rafiq, A., Kummer, W., Piper, H., et al. (2012) Intermedin (adrenomedullin2) stabilizes the endothelial barrier and antagonizes thrombin-induced barrier failure in endothelial cell monolayers, British Journal of Pharmacology, 165(1), pp. 208-222. https://doi.org/10.1111/j.1476-5381.2011.01540.x

APA-ZitierstilAslam, M., Pfeil, U., Guenduez, D., Rafiq, A., Kummer, W., Piper, H., & Noll, T. (2012). Intermedin (adrenomedullin2) stabilizes the endothelial barrier and antagonizes thrombin-induced barrier failure in endothelial cell monolayers. British Journal of Pharmacology. 165(1), 208-222. https://doi.org/10.1111/j.1476-5381.2011.01540.x



Schlagwörter


CALCITONIN-RECEPTORCAMP ACCUMULATIONCGRP8-37INDUCED INCREASEintermedinPEPTIDE FAMILY PEPTIDEPERMEABILITYRAMP2RECEPTOR-LIKE-RECEPTORTHROMBIN


Nachhaltigkeitsbezüge


Zuletzt aktualisiert 2025-10-06 um 10:03