Journal article

Intermedin (adrenomedullin2) stabilizes the endothelial barrier and antagonizes thrombin-induced barrier failure in endothelial cell monolayers


Authors listAslam, M.; Pfeil, U.; Guenduez, D.; Rafiq, A.; Kummer, W.; Piper, H. M.; Noll, T.

Publication year2012

Pages208-222

JournalBritish Journal of Pharmacology

Volume number165

Issue number1

ISSN0007-1188

Open access statusGreen

DOI Linkhttps://doi.org/10.1111/j.1476-5381.2011.01540.x

PublisherWiley


Abstract
BACKGROUND AND PURPOSE Intermedin is a member of the calcitonin gene-related-peptide (CGRP) family expressed in endothelial cells and acts via calcitonin receptor-like receptors (CLRs). Here we have analysed the receptors for intermedin and its effect on the endothelial barrier in monolayers of human umbilical vein endothelial cells (HUVECs).



Citation Styles

Harvard Citation styleAslam, M., Pfeil, U., Guenduez, D., Rafiq, A., Kummer, W., Piper, H., et al. (2012) Intermedin (adrenomedullin2) stabilizes the endothelial barrier and antagonizes thrombin-induced barrier failure in endothelial cell monolayers, British Journal of Pharmacology, 165(1), pp. 208-222. https://doi.org/10.1111/j.1476-5381.2011.01540.x

APA Citation styleAslam, M., Pfeil, U., Guenduez, D., Rafiq, A., Kummer, W., Piper, H., & Noll, T. (2012). Intermedin (adrenomedullin2) stabilizes the endothelial barrier and antagonizes thrombin-induced barrier failure in endothelial cell monolayers. British Journal of Pharmacology. 165(1), 208-222. https://doi.org/10.1111/j.1476-5381.2011.01540.x



Keywords


CALCITONIN-RECEPTORCAMP ACCUMULATIONCGRP8-37INDUCED INCREASEintermedinPEPTIDE FAMILY PEPTIDEPERMEABILITYRAMP2RECEPTOR-LIKE-RECEPTORTHROMBIN

Last updated on 2025-10-06 at 10:03