Journal article

Basics and principles in the application of Onyx LD liquid embolic system in the endovascular treatment of cerebral arteriovenous malformations


Authors listSiekmann, R

Publication year2005

Pages131-140

JournalInterventional Neuroradiology

Volume number11

Issue number1, Suppl.

ISSN1123-9344

Open access statusGreen

DOI Linkhttps://doi.org/10.1177/15910199050110S117

PublisherSAGE Publications


Abstract
Onyx is a new liquid embolic system (Micro Therapeutics, Inc., Irvine, CA) consisting of ethylene-vinyl alcohol copolymer (EVOH), formed of 48 mol/L ethylene and 52 mol/L vinyl alcohol, dissolved in dimethyl-sulfoxide (DMSO) and mixed with micronized tantalum powder (35% weight per volume) for radiopaque visualization. In its low density form it is predominantly used worldwide in the treatment of cerebral(1-6) or spinal(7.8) arteriovenous malformations (AVMs), other more rare indications are hypervascularized tumors(9), peripheral AVMs or arteriovenous fistulas (AVFs)(10), and there is also an extensive use in experimental work (11-12). Onyx LD means low density of EVOH in the range of 6 to 8 % (Onyx 18 to 34) compared to high density Onyx 500(+) (containing 20 % of EVOH) used for aneurysm occlusions. The basics of Onyx LD liquid system and the main principles of its application in endovascular AVM therapy are described and discussed in this chapter.



Citation Styles

Harvard Citation styleSiekmann, R. (2005) Basics and principles in the application of Onyx LD liquid embolic system in the endovascular treatment of cerebral arteriovenous malformations, Interventional Neuroradiology, 11(1, Suppl.), pp. 131-140. https://doi.org/10.1177/15910199050110S117

APA Citation styleSiekmann, R. (2005). Basics and principles in the application of Onyx LD liquid embolic system in the endovascular treatment of cerebral arteriovenous malformations. Interventional Neuroradiology. 11(1, Suppl.), 131-140. https://doi.org/10.1177/15910199050110S117



Keywords


AVMsEMBOLIZATIONtherapeutic neuroradiologyVINYL ALCOHOL COPOLYMER

Last updated on 2025-10-06 at 09:37