Journalartikel

Studies of interferences of apomorphine and its metabolites or decomposition products with immunochemical screening tests for legal and illicit drugs after therapeutic doses of apomorphine


AutorenlisteSchütz, H; Erdmann, F; Risse, M; Weiler, G

Jahr der Veröffentlichung2002

Seiten716-719

ZeitschriftArzneimittel-Forschung

Bandnummer52

Heftnummer9

ISSN0004-4172

eISSN1616-7066

VerlagThieme Publishing


Abstract
This study deals with the question of whether apomorphine (CAS 314-19-2; e.g. In Ixense(R)) and its metabolites or decomposition products interfere with the specificity of immunochemical screening tests (immunoassays) for legal and illicit drugs. It was the result of the investigations that after the therapeutic use of apomorphine no relevant false-positive screening findings were observed with the CEDIA (cloned enzyme donor immuno assay) and FPIA (fluorescence polarisation immuno assay) tests, which are commonly encountered in drug-screening programs, when using recommended cut-off values for urine.



Zitierstile

Harvard-ZitierstilSchütz, H., Erdmann, F., Risse, M. and Weiler, G. (2002) Studies of interferences of apomorphine and its metabolites or decomposition products with immunochemical screening tests for legal and illicit drugs after therapeutic doses of apomorphine, Arzneimittel-Forschung, 52(9), pp. 716-719

APA-ZitierstilSchütz, H., Erdmann, F., Risse, M., & Weiler, G. (2002). Studies of interferences of apomorphine and its metabolites or decomposition products with immunochemical screening tests for legal and illicit drugs after therapeutic doses of apomorphine. Arzneimittel-Forschung. 52(9), 716-719.



Schlagwörter


apomorphineCAS 314-19-2cloned enzyme donor immuno assayERECTILEfluorescence polarisation immuno assayimmunochemical screening tests, specificityIxense (R)SL

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