Journal article

Studies of interferences of apomorphine and its metabolites or decomposition products with immunochemical screening tests for legal and illicit drugs after therapeutic doses of apomorphine


Authors listSchütz, H; Erdmann, F; Risse, M; Weiler, G

Publication year2002

Pages716-719

JournalArzneimittel-Forschung

Volume number52

Issue number9

ISSN0004-4172

eISSN1616-7066

PublisherThieme Publishing


Abstract
This study deals with the question of whether apomorphine (CAS 314-19-2; e.g. In Ixense(R)) and its metabolites or decomposition products interfere with the specificity of immunochemical screening tests (immunoassays) for legal and illicit drugs. It was the result of the investigations that after the therapeutic use of apomorphine no relevant false-positive screening findings were observed with the CEDIA (cloned enzyme donor immuno assay) and FPIA (fluorescence polarisation immuno assay) tests, which are commonly encountered in drug-screening programs, when using recommended cut-off values for urine.



Citation Styles

Harvard Citation styleSchütz, H., Erdmann, F., Risse, M. and Weiler, G. (2002) Studies of interferences of apomorphine and its metabolites or decomposition products with immunochemical screening tests for legal and illicit drugs after therapeutic doses of apomorphine, Arzneimittel-Forschung, 52(9), pp. 716-719

APA Citation styleSchütz, H., Erdmann, F., Risse, M., & Weiler, G. (2002). Studies of interferences of apomorphine and its metabolites or decomposition products with immunochemical screening tests for legal and illicit drugs after therapeutic doses of apomorphine. Arzneimittel-Forschung. 52(9), 716-719.



Keywords


apomorphineCAS 314-19-2cloned enzyme donor immuno assayERECTILEfluorescence polarisation immuno assayimmunochemical screening tests, specificityIxense (R)SL

Last updated on 2025-02-04 at 04:25