Journalartikel

3-D confocal laser scanning microscopy used in morphometric analysis of rat Purkinje cell dendritic spines after chronic ethanol consumption


AutorenlisteWenisch, S; Fortmann, B; Steinmetz, T; Kriete, A; Leiser, R; Bitsch, I

Jahr der Veröffentlichung1998

Seiten393-397

ZeitschriftAnatomia, Histologia, Embryologia

Bandnummer27

Heftnummer6

ISSN0340-2096

eISSN1439-0264

DOI Linkhttps://doi.org/10.1111/j.1439-0264.1998.tb00213.x

VerlagWiley


Abstract
A confocal laser scanning microscope (with a 543 nm laser) was used for imaging rat Purkinje cell dendritic spines at high 3-D resolution In a nutritionally controlled study of the rat, 5 months of ethanol consumption was demonstrated to alter the spines of Purkinje cell dendrites in rat cerebellum Intact spines showed significant elongation after ethanol exposure, whereas this neuromorphological alteration could not be detected in controls. Spine elongation could be regarded as compensative growth of spines in search of new synaptic contacts due to alcohol induced cell loss.



Zitierstile

Harvard-ZitierstilWenisch, S., Fortmann, B., Steinmetz, T., Kriete, A., Leiser, R. and Bitsch, I. (1998) 3-D confocal laser scanning microscopy used in morphometric analysis of rat Purkinje cell dendritic spines after chronic ethanol consumption, Anatomia, Histologia, Embryologia, 27(6), pp. 393-397. https://doi.org/10.1111/j.1439-0264.1998.tb00213.x

APA-ZitierstilWenisch, S., Fortmann, B., Steinmetz, T., Kriete, A., Leiser, R., & Bitsch, I. (1998). 3-D confocal laser scanning microscopy used in morphometric analysis of rat Purkinje cell dendritic spines after chronic ethanol consumption. Anatomia, Histologia, Embryologia. 27(6), 393-397. https://doi.org/10.1111/j.1439-0264.1998.tb00213.x



Schlagwörter


ADULT-RATCEREBELLAR ATROPHYTERM ALCOHOL-CONSUMPTION


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