Journal article

3-D confocal laser scanning microscopy used in morphometric analysis of rat Purkinje cell dendritic spines after chronic ethanol consumption


Authors listWenisch, S; Fortmann, B; Steinmetz, T; Kriete, A; Leiser, R; Bitsch, I

Publication year1998

Pages393-397

JournalAnatomia, Histologia, Embryologia

Volume number27

Issue number6

ISSN0340-2096

eISSN1439-0264

DOI Linkhttps://doi.org/10.1111/j.1439-0264.1998.tb00213.x

PublisherWiley


Abstract
A confocal laser scanning microscope (with a 543 nm laser) was used for imaging rat Purkinje cell dendritic spines at high 3-D resolution In a nutritionally controlled study of the rat, 5 months of ethanol consumption was demonstrated to alter the spines of Purkinje cell dendrites in rat cerebellum Intact spines showed significant elongation after ethanol exposure, whereas this neuromorphological alteration could not be detected in controls. Spine elongation could be regarded as compensative growth of spines in search of new synaptic contacts due to alcohol induced cell loss.



Citation Styles

Harvard Citation styleWenisch, S., Fortmann, B., Steinmetz, T., Kriete, A., Leiser, R. and Bitsch, I. (1998) 3-D confocal laser scanning microscopy used in morphometric analysis of rat Purkinje cell dendritic spines after chronic ethanol consumption, Anatomia, Histologia, Embryologia, 27(6), pp. 393-397. https://doi.org/10.1111/j.1439-0264.1998.tb00213.x

APA Citation styleWenisch, S., Fortmann, B., Steinmetz, T., Kriete, A., Leiser, R., & Bitsch, I. (1998). 3-D confocal laser scanning microscopy used in morphometric analysis of rat Purkinje cell dendritic spines after chronic ethanol consumption. Anatomia, Histologia, Embryologia. 27(6), 393-397. https://doi.org/10.1111/j.1439-0264.1998.tb00213.x



Keywords


ADULT-RATCEREBELLAR ATROPHYTERM ALCOHOL-CONSUMPTION

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