Journal article

Cholinergic mechanisms in the neurocontrol of the branchial heart of the cephalopod Sepia officinalis L.


Authors listGebauer, M; Versen, B

Publication year1998

Pages13-20

JournalComparative Biochemistry and Physiology. Part C: Pharmacology, toxicology and endocrinology

Volume number119

Issue number1

ISSN1532-0456

eISSN1878-1659

DOI Linkhttps://doi.org/10.1016/S0742-8413(97)00162-X

PublisherElsevier


Abstract
Cholinergic mechanisms controlling the branchial heart of the cephalopod Sepia officinalis L. were examined. In vitro tests indicate that acetylcholine (ACh) exerts a dose dependent negative inotropic and chronotropic effect. Although the nicotinic agonists carbachol and nicotine mimic the effects of ACh closely, the muscarinic agonists pilocarpine, muscarine and oxotremorine induce only a slight inhibition of amplitude and frequency. Other agents tested (including atropine, pirencepine, hexamethonium, tetraethylammonium (TEA), d-tubocurarine and alpha-bungarotoxin) confirm chat the acetylcholine receptor in branchial heart muscle is probably nicotinic. (C) 1998 Elsevier Science Inc.



Citation Styles

Harvard Citation styleGebauer, M. and Versen, B. (1998) Cholinergic mechanisms in the neurocontrol of the branchial heart of the cephalopod Sepia officinalis L., Comparative Biochemistry and Physiology. Part C: Pharmacology, toxicology and endocrinology, 119(1), pp. 13-20. https://doi.org/10.1016/S0742-8413(97)00162-X

APA Citation styleGebauer, M., & Versen, B. (1998). Cholinergic mechanisms in the neurocontrol of the branchial heart of the cephalopod Sepia officinalis L.. Comparative Biochemistry and Physiology. Part C: Pharmacology, toxicology and endocrinology. 119(1), 13-20. https://doi.org/10.1016/S0742-8413(97)00162-X



Keywords


AGONISTSANTAGONISTSAPLYSIA NEURONSbranchial heartbungarotoxincephalopodinvertebratemolluscMONOAMINESnicotinic receptorpharmacologySepia

Last updated on 2025-02-04 at 06:45