Journal article
Authors list: Gebauer, M; Versen, B
Publication year: 1998
Pages: 13-20
Journal: Comparative Biochemistry and Physiology. Part C: Pharmacology, toxicology and endocrinology
Volume number: 119
Issue number: 1
ISSN: 1532-0456
eISSN: 1878-1659
DOI Link: https://doi.org/10.1016/S0742-8413(97)00162-X
Publisher: Elsevier
Abstract:
Cholinergic mechanisms controlling the branchial heart of the cephalopod Sepia officinalis L. were examined. In vitro tests indicate that acetylcholine (ACh) exerts a dose dependent negative inotropic and chronotropic effect. Although the nicotinic agonists carbachol and nicotine mimic the effects of ACh closely, the muscarinic agonists pilocarpine, muscarine and oxotremorine induce only a slight inhibition of amplitude and frequency. Other agents tested (including atropine, pirencepine, hexamethonium, tetraethylammonium (TEA), d-tubocurarine and alpha-bungarotoxin) confirm chat the acetylcholine receptor in branchial heart muscle is probably nicotinic. (C) 1998 Elsevier Science Inc.
Citation Styles
Harvard Citation style: Gebauer, M. and Versen, B. (1998) Cholinergic mechanisms in the neurocontrol of the branchial heart of the cephalopod Sepia officinalis L., Comparative Biochemistry and Physiology. Part C: Pharmacology, toxicology and endocrinology, 119(1), pp. 13-20. https://doi.org/10.1016/S0742-8413(97)00162-X
APA Citation style: Gebauer, M., & Versen, B. (1998). Cholinergic mechanisms in the neurocontrol of the branchial heart of the cephalopod Sepia officinalis L.. Comparative Biochemistry and Physiology. Part C: Pharmacology, toxicology and endocrinology. 119(1), 13-20. https://doi.org/10.1016/S0742-8413(97)00162-X
Keywords
AGONISTS; ANTAGONISTS; APLYSIA NEURONS; branchial heart; bungarotoxin; cephalopod; invertebrate; mollusc; MONOAMINES; nicotinic receptor; pharmacology; Sepia