Journalartikel

In-vitro-Evaluation des intravasalen Doppler-Führungsdrahtes: Bestimmung der hämodynamischen Auswirkungen von Stenosen in einem Flußmodell


AutorenlisteHoppe, M; Wagner, HJ; Kunisch, M; Froelich, JJ; Klose, KJ

Jahr der Veröffentlichung1997

Seiten544-549

ZeitschriftRöFo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren

Bandnummer166

Heftnummer6

ISSN0936-6652

DOI Linkhttps://doi.org/10.1055/s-2007-1015474

VerlagGeorg Thieme Verlag


Abstract
Purpose: In a pulsatile hydraulic model, haemodynamic changes caused by stenoses were assessed using an intravascular Doppler guide wire. Material and methods: In defined stenoses (25, 50, 75 and 87.5% diameter ratio), and with and without collateral flow, a 0.018 inch (0.46 mm) 12 MHz Doppler guide wire was assessed. Flow velocity measurements were taken 20 mm proximal, in, and 20 mm distal to the stenoses. Average peak velocity (APV) and ratios of pre-/poststenotic velocities and pre-/intrastenotic velocities of APV were compared with the grade of stenosis. The degree of the stenosis calculated by the ratio of the cross-sectional area, using the pre- and intrastenotic APV, was correlated with the actual stenosis. Results: The intrastenotic APV increased significantly (APV proximal to the stenosis 15.15 +/- 4.5 cm/s, intrastenotic APV 134.8 +/- 130.9, p < 0.01, Wilcoxon-Mann-Whitney test). The difference between APV pre- and poststenotic was not significant (p > 0.5). Concerning the grade of stenosis the ratio APV pre-lintrastenotic and the consecutively calculated cross-sectional area stenoses was the best predictor (correlation with the known cross-sectional area stenosis r=0.94 Pearson). Conclusion: Using the Doppler guide wire, APV measurements pre- and intrastenotic enable a reliable quantification of the grade of stenosis. The stenosis calculated via the cross-sectional area correlates significantly with the actual stenosis.


Zitierstile

Harvard-ZitierstilHoppe, M., Wagner, H., Kunisch, M., Froelich, J. and Klose, K. (1997) In-vitro-Evaluation des intravasalen Doppler-Führungsdrahtes: Bestimmung der hämodynamischen Auswirkungen von Stenosen in einem Flußmodell, RöFo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 166(6), pp. 544-549. https://doi.org/10.1055/s-2007-1015474

APA-ZitierstilHoppe, M., Wagner, H., Kunisch, M., Froelich, J., & Klose, K. (1997). In-vitro-Evaluation des intravasalen Doppler-Führungsdrahtes: Bestimmung der hämodynamischen Auswirkungen von Stenosen in einem Flußmodell. RöFo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. 166(6), 544-549. https://doi.org/10.1055/s-2007-1015474



Schlagwörter


ANGIOPLASTYflow modelflow velocity measurementsquantification of stenosis


Nachhaltigkeitsbezüge


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