Journal article
Authors list: Hoppe, M; Wagner, HJ; Kunisch, M; Froelich, JJ; Klose, KJ
Publication year: 1997
Pages: 544-549
Journal: RöFo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
Volume number: 166
Issue number: 6
ISSN: 0936-6652
DOI Link: https://doi.org/10.1055/s-2007-1015474
Publisher: Georg Thieme Verlag
Abstract:
Purpose: In a pulsatile hydraulic model, haemodynamic changes caused by stenoses were assessed using an intravascular Doppler guide wire. Material and methods: In defined stenoses (25, 50, 75 and 87.5% diameter ratio), and with and without collateral flow, a 0.018 inch (0.46 mm) 12 MHz Doppler guide wire was assessed. Flow velocity measurements were taken 20 mm proximal, in, and 20 mm distal to the stenoses. Average peak velocity (APV) and ratios of pre-/poststenotic velocities and pre-/intrastenotic velocities of APV were compared with the grade of stenosis. The degree of the stenosis calculated by the ratio of the cross-sectional area, using the pre- and intrastenotic APV, was correlated with the actual stenosis. Results: The intrastenotic APV increased significantly (APV proximal to the stenosis 15.15 +/- 4.5 cm/s, intrastenotic APV 134.8 +/- 130.9, p < 0.01, Wilcoxon-Mann-Whitney test). The difference between APV pre- and poststenotic was not significant (p > 0.5). Concerning the grade of stenosis the ratio APV pre-lintrastenotic and the consecutively calculated cross-sectional area stenoses was the best predictor (correlation with the known cross-sectional area stenosis r=0.94 Pearson). Conclusion: Using the Doppler guide wire, APV measurements pre- and intrastenotic enable a reliable quantification of the grade of stenosis. The stenosis calculated via the cross-sectional area correlates significantly with the actual stenosis.
Citation Styles
Harvard Citation style: Hoppe, M., Wagner, H., Kunisch, M., Froelich, J. and Klose, K. (1997) In-vitro-Evaluation des intravasalen Doppler-Führungsdrahtes: Bestimmung der hämodynamischen Auswirkungen von Stenosen in einem Flußmodell, RöFo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, 166(6), pp. 544-549. https://doi.org/10.1055/s-2007-1015474
APA Citation style: Hoppe, M., Wagner, H., Kunisch, M., Froelich, J., & Klose, K. (1997). In-vitro-Evaluation des intravasalen Doppler-Führungsdrahtes: Bestimmung der hämodynamischen Auswirkungen von Stenosen in einem Flußmodell. RöFo: Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. 166(6), 544-549. https://doi.org/10.1055/s-2007-1015474
Keywords
ANGIOPLASTY; flow model; flow velocity measurements; quantification of stenosis
