Journal article

HLA ASSOCIATION OF IDIOPATHIC PEYRONIES DISEASE - AN INDICATION OF AUTOIMMUNE PHENOMENA IN ETIOPATHOGENESIS


Authors listROMPEL, R; WEIDNER, W; MUELLERECKHARDT, G

Publication year1991

Pages104-106

JournalTissue Antigens

Volume number38

Issue number3

ISSN0001-2815

eISSN1399-0039

DOI Linkhttps://doi.org/10.1111/j.1399-0039.1991.tb02021.x

PublisherWiley: 12 months


Abstract
HLA typing for class I and class II antigens was done in 52 unrelated patients suffering from idiopathic Peyronie's disease. The controversially discussed association with the HLA-B7 cross-reacting group could not be confirmed. Marked deviations of antigen frequencies were observed for HLA-A1, B8, Cw7, DR3 and DQw2 compared to healthy local controls. After correction of p-values, A1 (p(c) < 0.05) and DQw2 (p(c) < 0.01) remained significant. A possible association of Peyronie's disease with markers of the HLA-A1, B8, Cw7, DR3, DQw2 haplotype, as first described here, would suggest autoimmunological factors in this disorder of otherwise unknown etiopathogenesis.



Citation Styles

Harvard Citation styleROMPEL, R., WEIDNER, W. and MUELLERECKHARDT, G. (1991) HLA ASSOCIATION OF IDIOPATHIC PEYRONIES DISEASE - AN INDICATION OF AUTOIMMUNE PHENOMENA IN ETIOPATHOGENESIS, Tissue Antigens, 38(3), pp. 104-106. https://doi.org/10.1111/j.1399-0039.1991.tb02021.x

APA Citation styleROMPEL, R., WEIDNER, W., & MUELLERECKHARDT, G. (1991). HLA ASSOCIATION OF IDIOPATHIC PEYRONIES DISEASE - AN INDICATION OF AUTOIMMUNE PHENOMENA IN ETIOPATHOGENESIS. Tissue Antigens. 38(3), 104-106. https://doi.org/10.1111/j.1399-0039.1991.tb02021.x



Keywords


ANTIGENSCLASS-IIHLA AND DISEASEHLA ANTIGENSPEYRONIES DISEASE

Last updated on 2025-02-04 at 05:57