Journal article

Publication year: 1990

Pages: 747-751

Journal: Journal of veterinary medicine. Series A: Physiology, pathology, clinical medicine

Volume number: 37

Issue number: 10

ISSN: 0931-184X

DOI Link: https://doi.org/10.1111/j.1439-0442.1990.tb00968.x

Publisher: Blackwell Verlag

Abstract: 
The aim of this investigation was to determine the radioiodine dose necessary for the ablation of the thyroid gland in male Wistar rats. By a mathematical extrapolation of the kinetics of iodine-131, the radioisotope does in the thyroid was calculated to be 467971 or 401540 rad after an intraperitoneal administration of 1 X 0.8 mCi (29.6 MBq) or 1 X 1.0 mCi (37.0 MBq) iodine-131, respectively. Because lower radioiodine activities did not result in a complete destruction of the thyroid (controlled by scintigraphic methods), it can be concluded that about 400 000 rad are necessary for the complete ablation of the thyroid gland by radioiodine.

Harvard Citation style: HANAUER, G. and SCHROTH, H. (1990) ESTIMATION OF THE RADIOIODINE DOSE NECESSARY FOR COMPLETE ABLATION OF THE THYROID-GLAND IN MALE WISTAR RATS, Journal of veterinary medicine. Series A, Physiology, pathology, clinical medicine, 37(10), pp. 747-751. https://doi.org/10.1111/j.1439-0442.1990.tb00968.x

APA Citation style: HANAUER, G., & SCHROTH, H. (1990). ESTIMATION OF THE RADIOIODINE DOSE NECESSARY FOR COMPLETE ABLATION OF THE THYROID-GLAND IN MALE WISTAR RATS. Journal of veterinary medicine. Series A, Physiology, pathology, clinical medicine. 37(10), 747-751. https://doi.org/10.1111/j.1439-0442.1990.tb00968.x