Journal article

DNA-DEPENDENT RNA POLYMERASE-II OF PLANT-ORIGIN TRANSCRIBES VIROID RNA INTO FULL-LENGTH COPIES


Authors list: RACKWITZ, HR; ROHDE, W; SANGER, HL

Publication year: 1981

Pages: 297-301

Journal: Nature

Volume number: 291

Issue number: 5813

ISSN: 0028-0836

eISSN: 1476-4687

DOI Link: https://doi.org/10.1038/291297a0

Publisher: Nature Research


Abstract: 
DNA-dependent RNA polymerase II purified from healthy plant [tomato, wheat germ] tissue is capable of synthesizing linear (-)-viroid RNA copies of full length from (+)-viroid RNA templates in vitro. Together with the specific .alpha.-amanitin sensitivity of viroid replication observed in vivo, these findings suggest that viroids replicate by an entirely novel mechanism in which infecting viroid RNA molecules are copied by the host enzyme, which is normally responsible for the synthesis of nuclear precursors to messenger RNA.



Citation Styles

Harvard Citation style: RACKWITZ, H., ROHDE, W. and SANGER, H. (1981) DNA-DEPENDENT RNA POLYMERASE-II OF PLANT-ORIGIN TRANSCRIBES VIROID RNA INTO FULL-LENGTH COPIES, Nature, 291(5813), pp. 297-301. https://doi.org/10.1038/291297a0

APA Citation style: RACKWITZ, H., ROHDE, W., & SANGER, H. (1981). DNA-DEPENDENT RNA POLYMERASE-II OF PLANT-ORIGIN TRANSCRIBES VIROID RNA INTO FULL-LENGTH COPIES. Nature. 291(5813), 297-301. https://doi.org/10.1038/291297a0



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