Journal article

Publication year: 1994

Pages: 261-267

Journal: Journal of Animal Physiology and Animal Nutrition

Volume number: 71

Issue number: 4-5

ISSN: 0931-2439

DOI Link: https://doi.org/10.1111/j.1439-0396.1994.tb00362.x

Publisher: Wiley

Abstract: 
The present study investigated the effect of lifibrol treatment (5 mg/kg and 10 mg/kg, respectively) on bile flow and bile composition in pigs. Lifibrol treatment reduced the rate of cholesterol secretion and cholesterol concentration as well as the lithogenic index of bile. The effect of lifibrol on these parameters was dose dependent. In contrast, bile flow, secretion rate and concentration of phospholipids and bile acids were not influenced by lifibrol treatment. The results indicate that lifibrol might be a useful agent in prevention gallstone formation.

Harvard Citation style: Kirchgeßner, M., Schliack, M., Spaulding, G., Eder, K., Löser, R., Seibel, K., et al. (1994) The effect of the hypolipidemic compound lifibrol on bile flow, bile lipids and the lithogenic index of bile in pigs, Journal of Animal Physiology and Animal Nutrition, 71(4-5), pp. 261-267. https://doi.org/10.1111/j.1439-0396.1994.tb00362.x

APA Citation style: Kirchgeßner, M., Schliack, M., Spaulding, G., Eder, K., Löser, R., Seibel, K., Erhardt, W., & Ascherl, R. (1994). The effect of the hypolipidemic compound lifibrol on bile flow, bile lipids and the lithogenic index of bile in pigs. Journal of Animal Physiology and Animal Nutrition. 71(4-5), 261-267. https://doi.org/10.1111/j.1439-0396.1994.tb00362.x