Journalartikel
Autorenliste: Ristivojevic, P.M.; Morlock, G.E.
Jahr der Veröffentlichung: 2018
Seiten: 344-353
Zeitschrift: Food Chemistry
Bandnummer: 260
Open Access Status: Green
DOI Link: https://doi.org/10.1016/j.foodchem.2018.03.127
Verlag: Elsevier
Biological and biochemical fingerprints were investigated for the first time for the feasibility of effect-directed classification, and thus, to allow the choice of a distinct beer with regard to beneficial health effects. A high-performance thin-layer chromatography method was newly developed and combined with in situ effect-directed analysis for profiling 50 German beers for multipotent active compounds, and thus, their health-related potential. Discovered multipotent active zones were online eluted and characterized by high resolution mass spectrometry. For example, isoxanthohumol, iso-alpha-ad/n-humulone or its isomers, desdimethyl-octahydro-isocohumulone and ad/n-humulone were proven as antimicrobial compounds, isoxanthohumol as an acetylcholinesterase inhibitor, and isoxanthohumol and iso-alpha-ad/n-humulone or its isomers as radical scavengers. Investigating multivariate data analysis of effect-directed fingerprints for the first time, the pattern recognition and classification results showed the power of clustering non-alcoholic beers from other types of beer, or it showed the differentiation of dark and non-alcoholic beers.
Abstract:
Zitierstile
Harvard-Zitierstil: Ristivojevic, P. and Morlock, G. (2018) Effect-directed classification of biological, biochemical and chemical profiles of 50 German beers, Food Chemistry, 260, pp. 344-353. https://doi.org/10.1016/j.foodchem.2018.03.127
APA-Zitierstil: Ristivojevic, P., & Morlock, G. (2018). Effect-directed classification of biological, biochemical and chemical profiles of 50 German beers. Food Chemistry. 260, 344-353. https://doi.org/10.1016/j.foodchem.2018.03.127