Journal article

Publication year: 2018

Pages: 344-353

Journal: Food Chemistry

Volume number: 260

Open access status: Green

DOI Link: https://doi.org/10.1016/j.foodchem.2018.03.127

Publisher: Elsevier

Abstract: 

Biological and biochemical fingerprints were investigated for the first time for the feasibility of effect-directed classification, and thus, to allow the choice of a distinct beer with regard to beneficial health effects. A high-performance thin-layer chromatography method was newly developed and combined with in situ effect-directed analysis for profiling 50 German beers for multipotent active compounds, and thus, their health-related potential. Discovered multipotent active zones were online eluted and characterized by high resolution mass spectrometry. For example, isoxanthohumol, iso-alpha-ad/n-humulone or its isomers, desdimethyl-octahydro-isocohumulone and ad/n-humulone were proven as antimicrobial compounds, isoxanthohumol as an acetylcholinesterase inhibitor, and isoxanthohumol and iso-alpha-ad/n-humulone or its isomers as radical scavengers. Investigating multivariate data analysis of effect-directed fingerprints for the first time, the pattern recognition and classification results showed the power of clustering non-alcoholic beers from other types of beer, or it showed the differentiation of dark and non-alcoholic beers.

Harvard Citation style: Ristivojevic, P. and Morlock, G. (2018) Effect-directed classification of biological, biochemical and chemical profiles of 50 German beers, Food Chemistry, 260, pp. 344-353. https://doi.org/10.1016/j.foodchem.2018.03.127

APA Citation style: Ristivojevic, P., & Morlock, G. (2018). Effect-directed classification of biological, biochemical and chemical profiles of 50 German beers. Food Chemistry. 260, 344-353. https://doi.org/10.1016/j.foodchem.2018.03.127