Journalartikel
Autorenliste: Fisch, KM; Schäberle, TF
Jahr der Veröffentlichung: 2016
Seiten: 683-691
Zeitschrift: Chemistry in Life Sciences
Bandnummer: 349
Heftnummer: 9
ISSN: 0365-6233
DOI Link: https://doi.org/10.1002/ardp.201600064
Verlag: Wiley-VCH Verlag
Abstract:
Microorganisms produce a vast array of biologically active metabolites. Such compounds are applied by humans to positively influence their health and, therefore, natural products serve as drug leads for pharmaceutical and medicinal chemistry. In this minireview, tools for the discovery and the production of potential drug leads are explained. A snapshot is provided, starting from the isolation of new producer strains, across genomic mining of (meta)genomes to identify biosynthetic gene clusters corresponding to natural products, toward heterologous expression to produce potential drug leads.
Zitierstile
Harvard-Zitierstil: Fisch, K. and Schäberle, T. (2016) Toolbox for Antibiotics Discovery from Microorganisms, Chemistry in Life Sciences, 349(9), pp. 683-691. https://doi.org/10.1002/ardp.201600064
APA-Zitierstil: Fisch, K., & Schäberle, T. (2016). Toolbox for Antibiotics Discovery from Microorganisms. Chemistry in Life Sciences. 349(9), 683-691. https://doi.org/10.1002/ardp.201600064
