Sammelbandbeitrag

Erschienen in: Encyclopedia of Analytical Science, Vol. 1: A - Che

Herausgeberliste: Worsfold, P.; Poole, C.; Townshend, A.; Miro, M.

Jahr der Veröffentlichung: 2019

Seiten: 261-270

ISBN: 978-0-08-101983-2

eISBN: 978-0-08-101984-9

DOI Link: https://doi.org/10.1016/B978-0-12-409547-2.13959-9

Auflage: 3rd edition

Abstract: 

The importance of a fast effect-directed profiling of samples is triggered by the global threat to ecosystems, global product chains and unknown active principles of food, cosmetics, and traditional medicines. Chromatography combined with effect-directed detections points to active compounds in complex samples. Effect-directed assays were performed in situ, postcolumn in flow and offline as standard in vitro assay after postcolumn fractionation. Among the possible combinations of chromatography with effect-directed assays, high-performance thin-layer chromatography turned out to be the most flexible chromatographic technique in combination with biochemical and especially biological assays. Powerful multidetection is used to characterize unknown active compounds discovered.

Harvard-Zitierstil: Morlock, G. (2019) Bioassays | Effects-Detection in Chromatography, in Worsfold, P., Poole, C., Townshend, A. and Miro, M. (eds.) Encyclopedia of Analytical Science, Vol. 1: A - Che. 3rd edition. Amsterdam: Elsevier, pp. 261-270. https://doi.org/10.1016/B978-0-12-409547-2.13959-9

APA-Zitierstil: Morlock, G. (2019). Bioassays | Effects-Detection in Chromatography. In Worsfold, P., Poole, C., Townshend, A., & Miro, M. (Eds.), Encyclopedia of Analytical Science, Vol. 1: A - Che (3rd edition, pp. 261-270). Elsevier. https://doi.org/10.1016/B978-0-12-409547-2.13959-9