Contribution in an anthology

Appeared in: Encyclopedia of Analytical Science, Vol. 1: A - Che

Editor list: Worsfold, P.; Poole, C.; Townshend, A.; Miro, M.

Publication year: 2019

Pages: 261-270

ISBN: 978-0-08-101983-2

eISBN: 978-0-08-101984-9

DOI Link: https://doi.org/10.1016/B978-0-12-409547-2.13959-9

Edition: 3rd edition

Abstract: 

The importance of a fast effect-directed profiling of samples is triggered by the global threat to ecosystems, global product chains and unknown active principles of food, cosmetics, and traditional medicines. Chromatography combined with effect-directed detections points to active compounds in complex samples. Effect-directed assays were performed in situ, postcolumn in flow and offline as standard in vitro assay after postcolumn fractionation. Among the possible combinations of chromatography with effect-directed assays, high-performance thin-layer chromatography turned out to be the most flexible chromatographic technique in combination with biochemical and especially biological assays. Powerful multidetection is used to characterize unknown active compounds discovered.

Harvard Citation style: Morlock, G. (2019) Bioassays | Effects-Detection in Chromatography, in Worsfold, P., Poole, C., Townshend, A. and Miro, M. (eds.) Encyclopedia of Analytical Science, Vol. 1: A - Che. 3rd edition. Amsterdam: Elsevier, pp. 261-270. https://doi.org/10.1016/B978-0-12-409547-2.13959-9

APA Citation style: Morlock, G. (2019). Bioassays | Effects-Detection in Chromatography. In Worsfold, P., Poole, C., Townshend, A., & Miro, M. (Eds.), Encyclopedia of Analytical Science, Vol. 1: A - Che (3rd edition, pp. 261-270). Elsevier. https://doi.org/10.1016/B978-0-12-409547-2.13959-9