Journalartikel

Three new andrastin derivatives from the endophytic fungus Penicillium vulpinum


AutorenlisteQin, YY; Huang, XS; Liu, XB; Mo, TX; Xu, ZL; Li, BC; Qin, XY; Li, J; Schäberle, TF; Yang, RY

Jahr der Veröffentlichung2022

Seiten3262-3270

ZeitschriftNatural Product Research

Bandnummer36

Heftnummer13

ISSN1478-6419

DOI Linkhttps://doi.org/10.1080/14786419.2020.1853725

VerlagTaylor and Francis Group


Abstract
Three new andrastin derivatives, 10-formyl andrastone A (1), 10-demethylated andrastone A (2) and andrastin G (3), together with four known andrastin analogues (4-7) were isolated from an endophytic fungus Penicillium vulpinum. Their structures were determined by 1 D, 2 D NMR, and the absolute configurations were further determined by experimental and calculated ECD spectra. Compound 5 exhibited significant antibacterial activity against Bacillus paratyphosus B with an MIC value of 6.25 mu g center dot mL(-1). Compounds 2 and 6 showed remarkable inhibitory activities against Bacillus megaterium with the MIC value of 6.25 mu g center dot mL(-1), respectively.



Zitierstile

Harvard-ZitierstilQin, Y., Huang, X., Liu, X., Mo, T., Xu, Z., Li, B., et al. (2022) Three new andrastin derivatives from the endophytic fungus Penicillium vulpinum, Natural Product Research, 36(13), pp. 3262-3270. https://doi.org/10.1080/14786419.2020.1853725

APA-ZitierstilQin, Y., Huang, X., Liu, X., Mo, T., Xu, Z., Li, B., Qin, X., Li, J., Schäberle, T., & Yang, R. (2022). Three new andrastin derivatives from the endophytic fungus Penicillium vulpinum. Natural Product Research. 36(13), 3262-3270. https://doi.org/10.1080/14786419.2020.1853725



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