Journal article

Publication year: 2022

Pages: 3262-3270

Journal: Natural Product Research

Volume number: 36

Issue number: 13

ISSN: 1478-6419

DOI Link: https://doi.org/10.1080/14786419.2020.1853725

Publisher: Taylor and Francis Group

Abstract: 
Three new andrastin derivatives, 10-formyl andrastone A (1), 10-demethylated andrastone A (2) and andrastin G (3), together with four known andrastin analogues (4-7) were isolated from an endophytic fungus Penicillium vulpinum. Their structures were determined by 1 D, 2 D NMR, and the absolute configurations were further determined by experimental and calculated ECD spectra. Compound 5 exhibited significant antibacterial activity against Bacillus paratyphosus B with an MIC value of 6.25 mu g center dot mL(-1). Compounds 2 and 6 showed remarkable inhibitory activities against Bacillus megaterium with the MIC value of 6.25 mu g center dot mL(-1), respectively.

Harvard Citation style: Qin, Y., Huang, X., Liu, X., Mo, T., Xu, Z., Li, B., et al. (2022) Three new andrastin derivatives from the endophytic fungus Penicillium vulpinum, Natural Product Research, 36(13), pp. 3262-3270. https://doi.org/10.1080/14786419.2020.1853725

APA Citation style: Qin, Y., Huang, X., Liu, X., Mo, T., Xu, Z., Li, B., Qin, X., Li, J., Schäberle, T., & Yang, R. (2022). Three new andrastin derivatives from the endophytic fungus Penicillium vulpinum. Natural Product Research. 36(13), 3262-3270. https://doi.org/10.1080/14786419.2020.1853725