Conference paper

Drug transporters in pharmacokinetics


Authors listPetzinger, E; Geyer, J

Publication year2006

Pages465-475

JournalNaunyn-Schmiedeberg's Archives of Pharmacology

Volume number372

Issue number6

ISSN0028-1298

eISSN1432-1912

DOI Linkhttps://doi.org/10.1007/s00210-006-0042-9

Conference5th Transport Colloquium

PublisherSpringer


Abstract
This review deals with the drug transporters allowing drugs to enter and leave cells by carrier-mediated pathways. Emphasis is put on liver transporters but systems in gut, kidney, and blood-brain barrier are mentioned as well. Drug-drug interactions on carriers may provoke significant modification in pharmacokinetics as do carrier gene polymorphisms yielding functional carrier protein mutations. An integrated phase concept should reflect the interplay between drug metabolism and drug transport.



Citation Styles

Harvard Citation stylePetzinger, E. and Geyer, J. (2006) Drug transporters in pharmacokinetics, Naunyn-Schmiedeberg's Archives of Pharmacology, 372(6), pp. 465-475. https://doi.org/10.1007/s00210-006-0042-9

APA Citation stylePetzinger, E., & Geyer, J. (2006). Drug transporters in pharmacokinetics. Naunyn-Schmiedeberg's Archives of Pharmacology. 372(6), 465-475. https://doi.org/10.1007/s00210-006-0042-9


Last updated on 2025-21-05 at 17:05