Konferenzpaper

Jahr der Veröffentlichung: 2006

Seiten: 465-475

Zeitschrift: Naunyn-Schmiedeberg's Archives of Pharmacology

Bandnummer: 372

Heftnummer: 6

ISSN: 0028-1298

eISSN: 1432-1912

DOI Link: https://doi.org/10.1007/s00210-006-0042-9

Konferenz: 5th Transport Colloquium

Verlag: Springer

Abstract: 
This review deals with the drug transporters allowing drugs to enter and leave cells by carrier-mediated pathways. Emphasis is put on liver transporters but systems in gut, kidney, and blood-brain barrier are mentioned as well. Drug-drug interactions on carriers may provoke significant modification in pharmacokinetics as do carrier gene polymorphisms yielding functional carrier protein mutations. An integrated phase concept should reflect the interplay between drug metabolism and drug transport.

Harvard-Zitierstil: Petzinger, E. and Geyer, J. (2006) Drug transporters in pharmacokinetics, Naunyn-Schmiedeberg's Archives of Pharmacology, 372(6), pp. 465-475. https://doi.org/10.1007/s00210-006-0042-9

APA-Zitierstil: Petzinger, E., & Geyer, J. (2006). Drug transporters in pharmacokinetics. Naunyn-Schmiedeberg's Archives of Pharmacology. 372(6), 465-475. https://doi.org/10.1007/s00210-006-0042-9