Journalartikel

Jahr der Veröffentlichung: 2023

Seiten: 707-710

Zeitschrift: Journal of Science and Medicine in Sport

Bandnummer: 26

Heftnummer: 12

ISSN: 1878-1861

DOI Link: https://doi.org/10.1016/j.jsams.2023.10.007

Verlag: Elsevier

Abstract: 
Interactions between statin therapy and physical exercise complicate effective cardiovascular prevention. Emerging evidence suggests that muscle strain related changes in the expression of the glucocorticoid-induced leucine zipper (GILZ) may be involved. Therefore, we measured GILZ mRNA expression levels in M. vastus lateralis samples of 32 healthy individuals before and after a standardized bout of strength or endurance exercise. Overall, we found a highly significant downregulation of GILZ after exercise training (p < 0.001). Within-subgroup changes were statistically significant only after strength training, supporting the role of muscle (as opposed to cardiocirculatory) strain. If confirmed, this may help fitting training recommendations and medication.

Harvard-Zitierstil: Hecksteden, A., Hoppstädter, J., Bizjak, D., Jerg, A., Kirsten, J., Krüger, K., et al. (2023) Effects of acute exercise and training status on glucocorticoid-induced leucine zipper (GILZ) expression in human skeletal muscle, Journal of Science and Medicine in Sport, 26(12), pp. 707-710. https://doi.org/10.1016/j.jsams.2023.10.007

APA-Zitierstil: Hecksteden, A., Hoppstädter, J., Bizjak, D., Jerg, A., Kirsten, J., Krüger, K., Niess, A., Steinacker, J., & Kiemer, A. (2023). Effects of acute exercise and training status on glucocorticoid-induced leucine zipper (GILZ) expression in human skeletal muscle. Journal of Science and Medicine in Sport. 26(12), 707-710. https://doi.org/10.1016/j.jsams.2023.10.007