Uni.-Prof. Dr. Sandra B. Hake
Projects as principal investigator
- Verständnis der funktionellen Rolle von ZNF512B in NuRD-abhängigen und -unabhängigen Chromatinprozessen
01/05/2024 - 30/04/2027
German Research Foundation (DFG) - Die funktionelle Rolle von HMG20A und dessen assoziierter Proteinkomplexe in der Regulation von Transkriptionsprogrammen in der Entwicklung
01/09/2023 - 31/08/2026
German Research Foundation (DFG) - Funktionelle und mechanistische Analyse des neuen H2A.Z-Bindeproteins MIER1
01/07/2022 - 30/09/2025
German Research Foundation (DFG) - Untersuchung zur evolutionären Transition der Nukleosomen Assemblierung
01/07/2022 - 30/09/2025
German Research Foundation (DFG) - Untersuchung der multivalenten Chromatin-Bindungseigenschaften von PWWP2A
18/07/2018 - 17/10/2021
German Research Foundation (DFG)
- PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex (2018)
- Nature Communications
Journal article - H3.Y discriminates between HIRA and DAXX chaperone complexes and reveals unexpected insights into human DAXX-H3.3-H4 binding and deposition requirements (2017)
- Nucleic Acids Research
Journal article - Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation (2017)
- The EMBO Journal
Journal article - PWWP2A: A novel mitosis link? (2017)
- Cell Cycle
Journal article - Variants of core histones and their roles in cell fate decisions, development and cancer. (2017)
- Nature Reviews Molecular Cell Biology
Journal article - Histone variant H2A.Z.2: A novel driver of melanoma progression (2016)
- Molecular & Cellular Oncology
Journal article - Histone variants: nuclear function and disease (2016)
- Current Opinion in Genetics & Development
Journal article - Histone Variant H2AZ2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma (2015)
- Molecular Cell
Journal article - The CENP-T C-terminus is exclusively proximal to H3.1 and not to H3.2 or H3.3. (2015)
- International Journal of Molecular Sciences
Journal article - Getting down to the core of histone modifications (2014)
- Chromosoma
Journal article - Histone glutamine methylation afFACTing rDNA transcription. (2014)
- Cell Research
Journal article - Structure-guided mutational analysis reveals the functional requirements for product specificity of DOT1 enzymes. (2014)
- Nature Communications
Journal article - The histone variant H2A.Bbd is enriched at sites of DNA synthesis (2014)
- Nucleic Acids Research
Journal article - H3K56me3 Is a Novel, Conserved Heterochromatic Mark That Largely but Not Completely Overlaps with H3K9me3 in Both Regulation and Localization (2013)
- PLoS ONE
Journal article - Histone h3 glutathionylation in proliferating mammalian cells destabilizes nucleosomal structure. (2013)
- Antioxidants & Redox Signaling
Journal article